# Nature Biomedical Engineering

Chinese Researchers Unveil Dye-Free Near‑Infrared Imaging That Sharpens Liver Tumour Margins in Surgery

Researchers at Fudan University and Huashan Hospital report a label‑free near‑infrared imaging technique (TANI) that visualizes liver tumour margins in real time without injected contrast. Published in Nature Biomedical Engineering, the method uses endogenous autofluorescence in the NIR‑II band to produce high‑contrast images while avoiding interference from blood, bile and cirrhosis.