# lactylation

Chinese teams unmask a metabolic immune‑escape — and a path toward lab‑made anti‑tumour T cells

Chinese research teams identified extracellular CD44 lactylation as a mechanism by which tumour‑generated lactate blunts CD8+ T cell function, revealing a direct metabolic route to immune escape. The discovery suggests new therapeutic strategies — including drugs or engineered T cells resistant to lactylation — but remains at the preclinical stage.